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Topamax saved my life. I am 43 years old and have suffered from migraines since I was 18. I found Topamax this past June. Now it has been 7 months and life without migraines is wonderful. No more fear of when the Big One will hit. The weight loss (20lbs) was nice too. My worst side effect is the stumbling and grasping for words. My kids die laughing. So do I. My husband doesn't understand that part but it's ok. As long as the headaches don't come. I still have small, treatable headaches (part of another problem that I hope soon goes away). Topamax is my hero. Take away my car, my clothes, my house...but don't take away my Topamax.

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At 12 months, the protocol analysis showed 48% of the SCS group and 9% of the CMM group were achieving at least 50% pain relief.

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In a pooled meta-analysis of a variety of exercise interventions, there was strong evidence of a fairly sizable short-term improvement in pain when patients used exercise therapy compared with no treatment.

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Trimethadione may also be used for purposes not listed in this medication guide.

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As with other anti-epileptic medications, selective developmental toxicity in animals, including craniofacial defects and limb malformations, have been noted during organogenesis.

Brandes JL, Kudrow D, Stark SR, O'Carroll CP, Adelman JU, O'Donnell FJ, et al.

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Because of these changes in practice and, also, because of some limited new data which suggest that the risk of cardiovascular disease with the use of oral contraceptives may now be less than previously observed, the Fertility and Maternal Health Drugs Advisory Committee was asked to review the topic in 1989.

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