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Does prednisone reduce uric acid? Prednisone lowers serum uric acid levels in patients with decompensated heart failure by increasing renal uric acid clearance. At the end of the study, only high-dose prednisone significantly reduced SUA, whereas low- and medium-dose prednisone and standard HF care had no effect on SUA.
Does colchicine affect kidney function? In patients with CKD, however, NSAIDs can cause acute worsening of eGFR and are contraindicated in all stages of CKD. Colchicine is excreted renally and can accumulate to toxic levels in renal impairment. Colchicine is not contraindicated, but dose adjustment and close monitoring is suggested.
Can different generic drugs work differently? Most people will never notice a difference. "According to the FDA, generic drugs do not need to contain the same inactive ingredients as the brand name product. Inactive ingredients are those that have nothing to do with the therapeutic action of the drug ; binding materials, dyes, preservatives, and flavoring agents.
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